methyl 6-(dimethylamino)-4-hydroxynaphthalene-2-carboxylate - Names and Identifiers
methyl 6-(dimethylamino)-4-hydroxynaphthalene-2-carboxylate - Physico-chemical Properties
Molecular Formula | C14H15NO3
|
Molar Mass | 245.27 |
Density | 1.239 |
Boling Point | 441.9°C at 760 mmHg |
Flash Point | 221.1°C |
Vapor Presure | 2.02E-08mmHg at 25°C |
Storage Condition | 2-8°C |
Refractive Index | 1.648 |
methyl 6-(dimethylamino)-4-hydroxynaphthalene-2-carboxylate - Introduction
methyl 6-(dimethylamino)-I, also known as methyl yellow (methyl 6-(dimethylamino)-I), is an organic compound.
Nature:
-Appearance: White to light yellow solid
-molecular formula: C17H19NO3
-Molecular weight: 285.34g/mol
-Melting point: 78-81 ° C
-Boiling point: 461.4 ° C
Use:
-Methyl Ester yellow is mainly used as dye and indicator. Because its molecular structure contains amine, hydroxyl and methyl groups, it can show strong fluorescence under alkaline conditions. Therefore, it is commonly used in biochemistry, medicine and molecular biology in the field of fluorescent dyes, such as DNA gel electrophoresis and cell imaging experiments, can be used to label proteins, nucleic acids, lipids and other biological molecules.
-Methyl Ester yellow can also be used as a biochemical sensor. It is colorless in acidic and neutral environments, but produces a fluorescent signal in alkaline environments, which can be used to monitor pH changes in the environment.
Method:
-Methyl Ester yellow is often obtained by the reaction of naphthol and isopropanol. First, naphthol is reacted with isopropanol under acidic conditions to obtain an esterified product, and then the hydroxyl group is replaced by a dimethylamino group by introducing methylamine and performing a nucleophilic substitution reaction under alkaline conditions, methyl Ester yellow was finally obtained.
Safety Information:
-Methyl Ester yellow should be handled to avoid contact with skin and eyes, and to ensure that the operation is carried out in a well-ventilated laboratory.
-It may be irritating to the skin and eyes, so rinse with plenty of water immediately after contact. If necessary, seek medical help.
-During storage and use, avoid contact with strong oxidants, acids and high temperature conditions to prevent dangerous reactions.
-Detailed safety guidelines and personal protective measures can be found in the Chemical Safety Data Sheet (MSDS).
Last Update:2024-04-10 22:29:15